Compile Data Set for Download or QSAR
Report error Found 165 Enz. Inhib. hit(s) with all data for entry = 50033864
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352863BDBM50352863(CHEMBL1824141)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352875BDBM50352875(CHEMBL1824344)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352854BDBM50352854(CHEMBL1824361)
Affinity DataEC50:  10nMAssay Description:Inhibition of BACE1 expressed in CHO cells expressing wild type human APP assessed as inhibition of amyloid beta-40 or 42 production by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352854BDBM50352854(CHEMBL1824361)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352852BDBM50352852(CHEMBL1824145)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352849BDBM50352849(CHEMBL1824360)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352884BDBM50352884(CHEMBL1824353)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352872BDBM50352872(CHEMBL1824341)
Affinity DataIC50: 16nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352872BDBM50352872(CHEMBL1824341)
Affinity DataIC50: 18nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352876BDBM50352876(CHEMBL1824345)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352865BDBM50352865(CHEMBL1824143)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352865BDBM50352865(CHEMBL1824143)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352861BDBM50352861(CHEMBL1824139)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352862BDBM50352862(CHEMBL1824140)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352874BDBM50352874(CHEMBL1824343)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352873BDBM50352873(CHEMBL1824342)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352847BDBM50352847(CHEMBL1824358)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352871BDBM50352871(CHEMBL1824340)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352873BDBM50352873(CHEMBL1824342)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352853BDBM50352853(CHEMBL1824338)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352868BDBM50352868(CHEMBL1824336)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352861BDBM50352861(CHEMBL1824139)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352867BDBM50352867(CHEMBL1824357)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352850BDBM50352850(CHEMBL1824335)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352860BDBM50352860(CHEMBL1824138)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352849BDBM50352849(CHEMBL1824360)
Affinity DataEC50:  30nMAssay Description:Inhibition of BACE1 expressed in CHO cells expressing wild type human APP assessed as inhibition of amyloid beta-40 or 42 production by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352862BDBM50352862(CHEMBL1824140)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352874BDBM50352874(CHEMBL1824343)
Affinity DataIC50: 36nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352857BDBM50352857(CHEMBL1824135)
Affinity DataIC50: 40nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352870BDBM50352870(CHEMBL1824339)
Affinity DataIC50: 40nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352886BDBM50352886(CHEMBL1824355)
Affinity DataIC50: 40nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352847BDBM50352847(CHEMBL1824358)
Affinity DataIC50: 40nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352871BDBM50352871(CHEMBL1824340)
Affinity DataIC50: 50nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352875BDBM50352875(CHEMBL1824344)
Affinity DataIC50: 50nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352869BDBM50352869(CHEMBL1824337)
Affinity DataIC50: 50nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352854BDBM50352854(CHEMBL1824361)
Affinity DataIC50: 50nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352885BDBM50352885(CHEMBL1824354)
Affinity DataIC50: 60nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352864BDBM50352864(CHEMBL1824142)
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352884BDBM50352884(CHEMBL1824353)
Affinity DataEC50:  70nMAssay Description:Inhibition of BACE1 expressed in CHO cells expressing wild type human APP assessed as inhibition of amyloid beta-40 or 42 production by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352884BDBM50352884(CHEMBL1824353)
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352877BDBM50352877(CHEMBL1824346)
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352849BDBM50352849(CHEMBL1824360)
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352859BDBM50352859(CHEMBL1824137)
Affinity DataIC50: 80nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352880BDBM50352880(CHEMBL1824349)
Affinity DataIC50: 80nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352882BDBM50352882(CHEMBL1824351)
Affinity DataIC50: 80nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352856BDBM50352856(CHEMBL1824134)
Affinity DataIC50: 80nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352866BDBM50352866(CHEMBL1824356)
Affinity DataIC50: 90nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352848BDBM50352848(CHEMBL1824359)
Affinity DataIC50: 90nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352855BDBM50352855(CHEMBL1824133)
Affinity DataIC50: 100nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352873BDBM50352873(CHEMBL1824342)
Affinity DataEC50:  110nMAssay Description:Inhibition of BACE1 expressed in CHO cells expressing wild type human APP assessed as inhibition of amyloid beta-40 or 42 production by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
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