Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50033961
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354642(CHEMBL1834204)
Affinity DataIC50:  14nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354637(CHEMBL1834440)
Affinity DataIC50:  14nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354639(CHEMBL1834201)
Affinity DataIC50:  17nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354638(CHEMBL1834200)
Affinity DataIC50:  18nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM20716((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM20716((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354641(CHEMBL1834203)
Affinity DataIC50:  25nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354631(CHEMBL1834433)
Affinity DataIC50:  28nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354629(CHEMBL1834431)
Affinity DataIC50:  30nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354634(CHEMBL1834436)
Affinity DataIC50:  32nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354633(CHEMBL1834435)
Affinity DataIC50:  51nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354636(CHEMBL1834438)
Affinity DataIC50:  57nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354640(CHEMBL1834202)
Affinity DataIC50:  64nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354630(CHEMBL1834432)
Affinity DataIC50:  72nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354643(CHEMBL1834206)
Affinity DataIC50:  73nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354632(CHEMBL1834434)
Affinity DataIC50:  88nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354635(CHEMBL1834437)
Affinity DataIC50:  99nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed