Found 11 Enz. Inhib. hit(s) with all data for entry = 50034030 TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 142nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 503nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis)
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataEC50: 4.10E+3nMAssay Description:Activation of human PXR in DPX2 cells after 24 hrs by microplate reader relative to controlMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataEC50: 2.10E+3nMAssay Description:Activation of human PXR in DPX2 cells after 24 hrs by microplate reader relative to controlMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataEC50: 5.60E+3nMAssay Description:Activation of human PXR in DPX2 cells after 24 hrs by microplate reader relative to controlMore data for this Ligand-Target Pair
3D Structure (crystal)