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Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50034092
TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50305768(2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piper...)
Affinity DataIC50:  2nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356891(CHEMBL1915541)
Affinity DataIC50:  6nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356892(CHEMBL1915542)
Affinity DataIC50:  12nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356893(CHEMBL1915543)
Affinity DataIC50:  19nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356908(CHEMBL1915557)
Affinity DataIC50:  21nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356907(CHEMBL1915556)
Affinity DataIC50:  49nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356906(CHEMBL1915555)
Affinity DataIC50:  56nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50301057(2-(4-(2-(trifluoromethyl)benzoyl)piperazin-1-yl)th...)
Affinity DataIC50:  100nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356908(CHEMBL1915557)
Affinity DataIC50:  212nMAssay Description:Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356898(CHEMBL1915548)
Affinity DataIC50:  216nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356903(CHEMBL1914470)
Affinity DataIC50:  343nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356897(CHEMBL1915547)
Affinity DataIC50:  552nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356906(CHEMBL1915555)
Affinity DataIC50:  694nMAssay Description:Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356905(CHEMBL1915554)
Affinity DataIC50:  719nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStearoyl-CoA desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356893(CHEMBL1915543)
Affinity DataIC50:  760nMAssay Description:Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356896(CHEMBL1915546)
Affinity DataIC50:  911nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356907(CHEMBL1915556)
Affinity DataIC50:  975nMAssay Description:Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356902(CHEMBL1915552)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356904(CHEMBL1915553)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356901(CHEMBL1915551)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356899(CHEMBL1915549)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStearoyl-CoA desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356906(CHEMBL1915555)
Affinity DataIC50:  6.31E+3nMAssay Description:Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356900(CHEMBL1915550)
Affinity DataIC50:  8.32E+3nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356893(CHEMBL1915543)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356895(CHEMBL1915545)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356894(CHEMBL1915544)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStearoyl-CoA desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356908(CHEMBL1915557)
Affinity DataIC50:  3.77E+4nMAssay Description:Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStearoyl-CoA desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356907(CHEMBL1915556)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed