Compile Data Set for Download or QSAR
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Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50034099
TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127832(3-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  2nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127844(3-Ethyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-in...)
Affinity DataKi:  5nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127838(1-Methyl-2-[2-methyl-4-(3-piperidin-1-yl-propoxy)-...)
Affinity DataKi:  11nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127841(2-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-indolizine...)
Affinity DataKi:  13nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127834(1-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  16nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127840(1-Ethyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-in...)
Affinity DataKi:  19nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127830(6-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  28nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127835(1-Phenethyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl...)
Affinity DataKi:  37nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127833(8-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  40nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127847(1-Phenyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  40nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127846(7-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  40nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127843(5-Methyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  46nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127845(2-[2-Methyl-4-(3-piperidin-1-yl-propoxy)-phenyl]-i...)
Affinity DataKi:  152nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127836(2-[2-(3-Piperidin-1-yl-propoxy)-phenyl]-indolizine...)
Affinity DataKi:  236nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50127842(2-[3-(3-Piperidin-1-yl-propoxy)-phenyl]-indolizine...)
Affinity DataKi:  308nMAssay Description:Antagonist activity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-P receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357014(CHEMBL1916636)
Affinity DataKi:  4.00E+4nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-P receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357011(CHEMBL1916633)
Affinity DataKi:  7.90E+4nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-P receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357013(CHEMBL1916635)
Affinity DataKi:  1.00E+5nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-K receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357013(CHEMBL1916635)
Affinity DataKi:  1.00E+5nMAssay Description:Displacement of [125I]NKA from human NK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-P receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357012(CHEMBL1916634)
Affinity DataKi:  1.58E+5nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-K receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357014(CHEMBL1916636)
Affinity DataKi:  2.50E+5nMAssay Description:Displacement of [125I]NKA from human NK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-K receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357012(CHEMBL1916634)
Affinity DataKi:  3.98E+5nMAssay Description:Displacement of [125I]NKA from human NK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSubstance-K receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357011(CHEMBL1916633)
Affinity DataKi: >3.00E+6nMAssay Description:Displacement of [125I]NKA from human NK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50085657(4-(1-Ethyl-pyrrolo[2,1,5-cd]indolizin-2-yl)-phenol...)
Affinity DataIC50:  9.5nMAssay Description:Agonist activity at estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAromatase(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50318405((Z)-6-(4-chlorophenyl)-7-(pyridin-3-ylmethylene)-6...)
Affinity DataIC50:  110nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAromatase(Human)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50070097((Z)-6-(4-chlorophenyl)-7-(pyridin-4-ylmethylene)-6...)
Affinity DataIC50:  150nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357002(CHEMBL1916429)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357009(CHEMBL1916445)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357005(CHEMBL1916437)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357000(CHEMBL1916426)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357008(CHEMBL1916444)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357007(CHEMBL1914479)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357004(CHEMBL1916435)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357010(CHEMBL1916447)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357016(CHEMBL1916417)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357001(CHEMBL1916428)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357006(CHEMBL1916443)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357003(CHEMBL1916430)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
University of Botswana

Curated by ChEMBL
LigandPNGBDBM50357015(CHEMBL1916418)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed