Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50034386
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
3D Structure (crystal)TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of GlyT1 in human JAR cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid scintillat...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataIC50: 314nMAssay Description:Inhibition of human GlyT1 expressed in CHO cells assessed as inhibition of [3H]glycine uptake preincubated for 1 mins measured after 2 hrs by liquid ...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Binding affinity to GlyT1 in rat cortical brain homogenate after 60 mins by gamma countingMore data for this Ligand-Target Pair
