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Found 41 Enz. Inhib. hit(s) with all data for entry = 50034318
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  1nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  1nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360457(CHEMBL1934623)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360459(CHEMBL1934625)
Affinity DataIC50:  7nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360458(CHEMBL1934624)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360457(CHEMBL1934623)
Affinity DataIC50:  18nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360456(CHEMBL1934622)
Affinity DataIC50:  22nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360466(CHEMBL1934632)
Affinity DataIC50:  24nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360461(CHEMBL1934628)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360466(CHEMBL1934632)
Affinity DataIC50:  30nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360459(CHEMBL1934625)
Affinity DataIC50:  41nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360458(CHEMBL1934624)
Affinity DataIC50:  41nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360463(CHEMBL1933083)
Affinity DataIC50:  55nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50:  62nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360463(CHEMBL1933083)
Affinity DataIC50:  73nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360462(CHEMBL1934629)
Affinity DataIC50:  74nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360460(CHEMBL1934627)
Affinity DataIC50:  79nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360464(CHEMBL1934630)
Affinity DataIC50:  86nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360467(CHEMBL1934633)
Affinity DataIC50:  86nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360465(CHEMBL1934631)
Affinity DataIC50:  94nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360467(CHEMBL1934633)
Affinity DataIC50:  98nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360462(CHEMBL1934629)
Affinity DataIC50:  110nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360465(CHEMBL1934631)
Affinity DataIC50:  120nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360464(CHEMBL1934630)
Affinity DataIC50:  130nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360460(CHEMBL1934627)
Affinity DataIC50:  140nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360461(CHEMBL1934628)
Affinity DataIC50:  180nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50:  190nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360456(CHEMBL1934622)
Affinity DataIC50:  220nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360455(CHEMBL1934621)
Affinity DataIC50:  650nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360455(CHEMBL1934621)
Affinity DataIC50:  750nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  760nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed