Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50034326
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360580(CHEMBL1933343)
Affinity DataIC50:  22nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM17053(BX-320 | N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcar...)
Affinity DataIC50:  39nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  58nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360583(CHEMBL1933346)
Affinity DataIC50:  98nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360580(CHEMBL1933343)
Affinity DataIC50:  150nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360580(CHEMBL1933343)
Affinity DataIC50:  180nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360583(CHEMBL1933346)
Affinity DataIC50:  330nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360583(CHEMBL1933346)
Affinity DataIC50:  350nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  390nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  450nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  830nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360580(CHEMBL1933343)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM17053(BX-320 | N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcar...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360583(CHEMBL1933346)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed