Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50034333
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360722(CHEMBL1934294)
Affinity DataIC50:  24nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360723(CHEMBL1934295)
Affinity DataIC50:  29nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360723(CHEMBL1934295)
Affinity DataIC50:  29nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360724(CHEMBL1934296)
Affinity DataIC50:  36nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360721(CHEMBL1934293)
Affinity DataIC50:  70nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360724(CHEMBL1934296)
Affinity DataIC50:  100nMAssay Description:Inhibition of human BACE1 expressed in mouse fibroblast cells assessed as inhibition of soluble APPbeta_NF cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360720(CHEMBL1934292)
Affinity DataIC50:  150nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360723(CHEMBL1934295)
Affinity DataIC50:  570nMAssay Description:Inhibition of human BACE1 expressed in mouse fibroblast cells assessed as inhibition of soluble APPbeta_NF cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360717(CHEMBL1934289)
Affinity DataIC50:  600nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360722(CHEMBL1934294)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human BACE1 expressed in mouse fibroblast cells assessed as inhibition of soluble APPbeta_NF cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360719(CHEMBL1934291)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360714(CHEMBL1934286)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360723(CHEMBL1934295)
Affinity DataIC50:  6.21E+3nMAssay Description:Inhibition of Cat DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360716(CHEMBL1934288)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360718(CHEMBL1934290)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360713(CHEMBL1934285)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360715(CHEMBL1934287)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360723(CHEMBL1934295)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50360712(CHEMBL1934284)
Affinity DataIC50:  2.40E+5nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed