Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50034364
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataEC50:  129nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in DU145 cells assessed as increase in cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50026625(CHEMBL2068577)
Affinity DataEC50:  138nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50361247(Levalbuterol | Levolin | LEVOSALBUTAMOL | ALBUTERO...)
Affinity DataEC50:  145nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50026626(CHEMBL2068576)
Affinity DataEC50:  166nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50361247(Levalbuterol | Levolin | LEVOSALBUTAMOL | ALBUTERO...)
Affinity DataEC50:  275nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50361247(Levalbuterol | Levolin | LEVOSALBUTAMOL | ALBUTERO...)
Affinity DataEC50:  457nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(Isoproterenol,(+) | CHEMBL434 | 4-[1-hydroxy-2-(pr...)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50361247(Levalbuterol | Levolin | LEVOSALBUTAMOL | ALBUTERO...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells in presence of 100 uM boric acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50026626(CHEMBL2068576)
Affinity DataKi:  3.89E+3nMAssay Description:Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50361247(Levalbuterol | Levolin | LEVOSALBUTAMOL | ALBUTERO...)
Affinity DataKi:  4.68E+3nMAssay Description:Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells in presence of 100 uM phenylboronic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50361247(Levalbuterol | Levolin | LEVOSALBUTAMOL | ALBUTERO...)
Affinity DataKi:  5.62E+3nMAssay Description:Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50026625(CHEMBL2068577)
Affinity DataKi:  6.61E+3nMAssay Description:Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed