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Found 10 Enz. Inhib. hit(s) with all data for entry = 50034371
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50361331(CHEMBL1933276)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50361332(CHEMBL1933420)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50273710(2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...)
Affinity DataIC50:  650nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  670nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 0 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 0 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed