BindingDB PrimarySearch

Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50035847

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014354(6-[4,4-Bis-(4-fluoro-phenyl)-3-(1-methyl-1H-tetraz...)

IC50: 24nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM34168(LOVASTATIN | MLS000069585 | SMR000058779 | US91151...)

IC50: 27nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase ChEBI
DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014356(CHEMBL320666 | Sodium; 9,9-bis-(4-fluoro-2-methyl-...)

IC50: 29nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM34168(LOVASTATIN | MLS000069585 | SMR000058779 | US91151...)

IC50: 32nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase ChEBI
DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)

IC50: 43nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014358(CHEMBL103192 | Sodium; 9-(4-fluoro-phenyl)-3,5-dih...)

IC50: 44nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014355(CHEMBL103585 | Sodium; 7-(4'-fluoro-3,5,3'-trimeth...)

IC50: 52nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014365(CHEMBL103547 | Sodium; 9,9-bis-(4-fluoro-3-methyl-...)

IC50: 160nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014361(CHEMBL318754 | Sodium; 3,5-dihydroxy-8-(1-methyl-1...)

IC50: 190nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014364(CHEMBL318102 | Sodium; 8-[bis-(4-fluoro-phenyl)-me...)

IC50: 230nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014363(CHEMBL419542 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)

IC50: 330nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014349(CHEMBL328846 | Sodium; 9,9-bis-(2-fluoro-4-methyl-...)

IC50: 580nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014362(CHEMBL103661 | Sodium; 8-(1-ethyl-1H-tetrazol-5-yl...)

IC50: 1.10E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014346(CHEMBL441642 | Sodium; 3,5-dihydroxy-8-(1-methyl-1...)

IC50: 1.30E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014350(CHEMBL323075 | Sodium; 3,5-dihydroxy-9,9-bis-(4-me...)

IC50: 1.40E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014348(CHEMBL100188 | Sodium; 9,9-bis-(2,4-dimethyl-pheny...)

IC50: 1.60E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014351(CHEMBL323373 | Sodium; 8-(2-tert-butyl-2H-tetrazol...)

IC50: 3.70E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014351(CHEMBL323373 | Sodium; 8-(2-tert-butyl-2H-tetrazol...)

IC50: 3.70E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50421879(CHEMBL2304072)

IC50: 5.70E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014357(CHEMBL318256 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)

IC50: 7.90E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014360(CHEMBL322399 | Sodium; 8-cyano-9,9-bis-(4-fluoro-p...)

IC50: 8.00E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014353(CHEMBL319739 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)

IC50: 1.40E+4nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014352(CHEMBL102468 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)

IC50: 3.00E+4nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014367(CHEMBL103792 | Sodium; 10,10-bis-(4-fluoro-phenyl)...)

IC50: 1.30E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014366(CHEMBL102484 | Sodium; 8-(2-ethyl-2H-tetrazol-5-yl...)

IC50: 2.00E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014347(CHEMBL321715 | Sodium; 9,9-bis-(4-fluoro-phenyl)-3...)

IC50: >3.00E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Bristol-Myers Squibb

Curated by ChEMBL

BDBM50014345(CHEMBL11804 | Sodium; (E)-(3R,5S)-9,9-bis-(4-fluor...)

IC50: >3.00E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed