Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50039528
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100152BDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 30nMAssay Description:Inhibition of DYRK1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379521BDBM50379521(CHEMBL2012574)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379526BDBM50379526(CHEMBL2012563)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379512BDBM50379512(CHEMBL2012559)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379525BDBM50379525(CHEMBL2012562)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379516BDBM50379516(CHEMBL2012569)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379522BDBM50379522(CHEMBL2012575)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379511BDBM50379511(CHEMBL2012560)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379519BDBM50379519(CHEMBL2012572)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379523BDBM50379523(CHEMBL2012558)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379524BDBM50379524(CHEMBL2012561)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379520BDBM50379520(CHEMBL2012573)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379517BDBM50379517(CHEMBL2012570)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379527BDBM50379527(CHEMBL2012564)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100152BDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379528BDBM50379528(CHEMBL2012565)
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100152BDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 690nMAssay Description:Inhibition of DYRK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50778BDBM50778(MLS000028120 | cid_658017 | ethyl (1S,2S,3R,8aS)-3...)
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379518BDBM50379518(CHEMBL2012571)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50778BDBM50778(MLS000028120 | cid_658017 | ethyl (1S,2S,3R,8aS)-3...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of DYRK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379515BDBM50379515(CHEMBL2012568)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379514BDBM50379514(CHEMBL2012567)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379513BDBM50379513(CHEMBL2012566)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379517BDBM50379517(CHEMBL2012570)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379515BDBM50379515(CHEMBL2012568)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379514BDBM50379514(CHEMBL2012567)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379518BDBM50379518(CHEMBL2012571)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379522BDBM50379522(CHEMBL2012575)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379516BDBM50379516(CHEMBL2012569)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379520BDBM50379520(CHEMBL2012573)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379519BDBM50379519(CHEMBL2012572)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379523BDBM50379523(CHEMBL2012558)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379524BDBM50379524(CHEMBL2012561)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379511BDBM50379511(CHEMBL2012560)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379512BDBM50379512(CHEMBL2012559)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379526BDBM50379526(CHEMBL2012563)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379525BDBM50379525(CHEMBL2012562)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379528BDBM50379528(CHEMBL2012565)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379527BDBM50379527(CHEMBL2012564)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379513BDBM50379513(CHEMBL2012566)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379521BDBM50379521(CHEMBL2012574)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed