Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50034651
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315213BDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant PI3Kdelta HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315213BDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315213BDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant PI3Kbeta HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315213BDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant PI3Kgamma HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365736BDBM50365736(CHEMBL1956189)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365735BDBM50365735(MKT-077 | CHEMBL33859 | US20230414581, Compound 39)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203126BDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed