Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50039552
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379853BDBM50379853(CHEMBL2011854)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379853BDBM50379853(CHEMBL2011854)
Affinity DataIC50: 5nMAssay Description:Inhibition of HSP90 in human A375 cells assessed as induction of HSP70 synthesis after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379853BDBM50379853(CHEMBL2011854)
Affinity DataIC50: 11nMAssay Description:Inhibition of HSP90-mediated pS6 phosphorylation in human A375 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379853BDBM50379853(CHEMBL2011854)
Affinity DataIC50: 36nMAssay Description:Inhibition of HSP90-mediated Erk phosphorylation in human AU565 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379848BDBM50379848(CHEMBL2011850)
Affinity DataIC50: 401nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379854BDBM50379854(CHEMBL2011855)
Affinity DataIC50: 498nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379841BDBM50379841(CHEMBL2011843)
Affinity DataIC50: 568nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379845BDBM50379845(CHEMBL2011847)
Affinity DataIC50: 665nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379840BDBM50379840(CHEMBL2011853)
Affinity DataIC50: 705nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379842BDBM50379842(CHEMBL2011845)
Affinity DataIC50: 731nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379843BDBM50379843(CHEMBL2011846)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379849BDBM50379849(CHEMBL2011851)
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379857BDBM50379857(CHEMBL2011858)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379855BDBM50379855(CHEMBL2011856)
Affinity DataIC50: 4.51E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379852BDBM50379852(CHEMBL2011844)
Affinity DataIC50: 5.81E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379846BDBM50379846(CHEMBL2011848)
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379847BDBM50379847(CHEMBL2011849)
Affinity DataIC50: 7.75E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379851BDBM50379851(CHEMBL2011842)
Affinity DataIC50: 9.97E+3nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379858BDBM50379858(CHEMBL2011859)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379856BDBM50379856(CHEMBL2011857)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379844BDBM50379844(CHEMBL2010814)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379850BDBM50379850(CHEMBL2011852)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379859BDBM50379859(CHEMBL2011860)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed