Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50039940
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098106BDBM50098106(CHEMBL24259 | phenyl sulfamate | Sulfamic acid phe...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098108BDBM50098108(Sulfamic acid 4-bromo-phenyl ester | CHEMBL283121)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10870BDBM10870(aminobenzolamide deriv. 43 | CHEMBL268439 | 2-N-(4...)
Affinity DataKi:  2nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10885BDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)
Affinity DataKi:  3nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10882BDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKi:  8nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10884BDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10886BDBM10886(BZA1 | CHEMBL73962 | 2-N-benzene-1,3,4-thiadiazole...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10887BDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKi:  10nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10875BDBM10875(5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide...)
Affinity DataKi:  12nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  12nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124170BDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKi:  13nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10881BDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataKi:  14nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10890BDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataKi:  15nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10869BDBM10869(CHEMBL6753 | 5-imino-4-methyl-4,5-dihydro-1,3,4-th...)
Affinity DataKi:  19nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataKi:  21nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124178BDBM50124178(N-(4-bromophenyl)sulfamide | CHEMBL166686)
Affinity DataKi:  23nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10873BDBM10873(4-[(2-aminopyrimidin-4-yl)amino]benzene-1-sulfonam...)
Affinity DataKi:  33nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10888BDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  35nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10883BDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataKi:  38nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11638BDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataKi:  40nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10864BDBM10864(4-Amino-3-bromobenzenesulfonamide | 4-amino-3-brom...)
Affinity DataKi:  40nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13063BDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataKi:  43nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10871BDBM10871(CHEMBL266026 | 4-amino-N-[(4-sulfamoylphenyl)methy...)
Affinity DataKi:  46nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10872BDBM10872(4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-su...)
Affinity DataKi:  50nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10868BDBM10868(1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...)
Affinity DataKi:  60nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10862BDBM10862(CHEMBL6853 | 4-Amino-3-fluorobenzenesulfonamide | ...)
Affinity DataKi:  60nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10866BDBM10866(4-amino-6-(trifluoromethyl)benzene-1,3-disulfonami...)
Affinity DataKi:  63nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10865BDBM10865(4-amino-3-iodobenzene-1-sulfonamide | CHEMBL268177...)
Affinity DataKi:  70nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10867BDBM10867(4-amino-6-chlorobenzene-1,3-disulfonamide | CHEMBL...)
Affinity DataKi:  75nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10876BDBM10876(4-(hydroxymethyl)benzene-1-sulfonamide | JMC523116...)
Affinity DataKi:  80nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81918BDBM81918(p-Halide-sulfanilamide derivative, 2a)
Affinity DataKi:  81nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10863BDBM10863(4-Amino-3-chlorobenzenesulfonamide | 4-amino-3-chl...)
Affinity DataKi:  110nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10877BDBM10877(CHEMBL6784 | 4-(2-hydroxyethyl)benzene-1-sulfonami...)
Affinity DataKi:  125nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4703BDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Affinity DataKi:  133nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10861BDBM10861(aromatic sulfonamide compound 7 | CHEMBL7087 | 4-(...)
Affinity DataKi:  160nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10860BDBM10860(aromatic sulfonamide compound 6 | 4-(aminomethyl)b...)
Affinity DataKi:  170nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10857BDBM10857(aromatic sulfonamide compound 5 | CHEMBL21 | 4-ami...)
Affinity DataKi:  240nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  250nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10855BDBM10855(orthanilamide 17 | CHEMBL6705 | 2-aminobenzene-1-s...)
Affinity DataKi:  295nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12414BDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKi:  305nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10859BDBM10859(CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...)
Affinity DataKi:  320nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Union Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29277BDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  495nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed