Compile Data Set for Download or QSAR
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Found 75 Enz. Inhib. hit(s) with all data for entry = 50039630
LigandPNGBDBM50381156(CHEMBL2018220 | D3RKN_94)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381161(CHEMBL2018219)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381157(CHEMBL2018360)
Affinity DataIC50:  1nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381162(CHEMBL2018221)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381164(CHEMBL2018214)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50365868(CHEMBL1957857)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381161(CHEMBL2018219)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381165(CHEMBL2018215)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381163(CHEMBL2018361)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381155(CHEMBL2018216)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381162(CHEMBL2018221)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381156(CHEMBL2018220 | D3RKN_94)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50365868(CHEMBL1957857)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381160(CHEMBL2018218)
Affinity DataIC50:  13nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381165(CHEMBL2018215)
Affinity DataIC50:  13nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381155(CHEMBL2018216)
Affinity DataIC50:  20nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381161(CHEMBL2018219)
Affinity DataIC50:  20nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3Kbeta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381157(CHEMBL2018360)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381156(CHEMBL2018220 | D3RKN_94)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381165(CHEMBL2018215)
Affinity DataIC50:  31nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381164(CHEMBL2018214)
Affinity DataIC50:  34nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381162(CHEMBL2018221)
Affinity DataIC50:  40nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381164(CHEMBL2018214)
Affinity DataIC50:  50nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  63nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50365868(CHEMBL1957857)
Affinity DataIC50:  78nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381160(CHEMBL2018218)
Affinity DataIC50:  79nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381163(CHEMBL2018361)
Affinity DataIC50:  92nMAssay Description:Inhibition of PI3K beta-mediated AKT phosphorylation at serine 473 in PTEN deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381155(CHEMBL2018216)
Affinity DataIC50:  130nMAssay Description:Inhibition of PI3Kdelta by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  160nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381158(CHEMBL2018222)
Affinity DataIC50:  160nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381157(CHEMBL2018360)
Affinity DataIC50:  200nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  250nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  250nMAssay Description:Inhibition of PI3Kgamma by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381156(CHEMBL2018220 | D3RKN_94)
Affinity DataIC50:  320nMAssay Description:Inhibition of PI3Kalpha by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  320nMAssay Description:Inhibition of PI3Kalpha by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50381159(CHEMBL2018217)
Affinity DataIC50:  320nMAssay Description:Inhibition of PI3Kalpha by continuous read time resolved fluorescence resonance energy transfer displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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