Compile Data Set for Download or QSAR
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Found 91 Enz. Inhib. hit(s) with all data for entry = 50040053
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388546(CHEMBL213072 | CHEMBL333363)
Affinity DataKi:  3.19E+3nMAssay Description:Competitive inhibition of human recombinant Tdp1 after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388544(CHEMBL2057323)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388544(CHEMBL2057323)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50158383(2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388554(CHEMBL223545)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388554(CHEMBL223545)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388553(CHEMBL223773)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388555(CHEMBL388801)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388548(CHEMBL1182248 | CHEMBL225093)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388553(CHEMBL223773)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388547(CHEMBL1181663 | CHEMBL187863)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388547(CHEMBL1181663 | CHEMBL187863)
Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388549(CHEMBL1185123 | CHEMBL390611)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388548(CHEMBL1182248 | CHEMBL225093)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388551(CHEMBL225390)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388546(CHEMBL213072 | CHEMBL333363)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388546(CHEMBL213072 | CHEMBL333363)
Affinity DataIC50:  2.95E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388602(FURAMIDINE)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Tdp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388551(CHEMBL225390)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388555(CHEMBL388801)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388549(CHEMBL1185123 | CHEMBL390611)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388552(CHEMBL376179)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388552(CHEMBL376179)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388550(CHEMBL427251)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388550(CHEMBL427251)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388545(CHEMBL1181674 | CHEMBL188130)
Affinity DataIC50:  5.53E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388545(CHEMBL1181674 | CHEMBL188130)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388556(CHEMBL2059278)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388557(CHEMBL2059279)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM47063(CHEMBL2059280 | US8912213, 84)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388559(CHEMBL2059281)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388560(CHEMBL2059283)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388561(CHEMBL2059284)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388562(CHEMBL2059427)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388563(CHEMBL2059429)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388564(CHEMBL2059430)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388565(CHEMBL2059431)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388566(CHEMBL2059432)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388567(CHEMBL2059434)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388568(CHEMBL2059530)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388569(CHEMBL2059531)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388570(CHEMBL2059532)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388571(CHEMBL2059534)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388572(CHEMBL2059535)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388573(CHEMBL2059536)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388574(CHEMBL2059538)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388575(CHEMBL2059539)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388576(CHEMBL2059690)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388577(CHEMBL2059692)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388578(CHEMBL2059694)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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