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Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50039859
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50350023(CHEMBL1813065)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385250(CHEMBL2037609)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50350023(CHEMBL1813065)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385244(CHEMBL2037610)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385250(CHEMBL2037609)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385244(CHEMBL2037610)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385245(CHEMBL2037611)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385248(CHEMBL2037606)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385247(CHEMBL2037605)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385248(CHEMBL2037606)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385247(CHEMBL2037605)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385249(CHEMBL2037607)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from human histamine H3 receptor expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385245(CHEMBL2037611)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385249(CHEMBL2037607)
Affinity DataKi:  131nMAssay Description:Displacement of [3H]-Nalpha-methylhistamine from rat histamine H3 receptor expressed in CHO-A3 cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H1 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H1 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H2 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H4 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H4 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H2 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50350023(CHEMBL1813065)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385243(CHEMBL2037608)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50385246(CHEMBL2037604)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed