Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50039782
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21724BDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384048BDBM50384048(CHEMBL2032446)
Affinity DataEC50:  410nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21716BDBM21716(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  840nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384052BDBM50384052(CHEMBL2017541)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21715BDBM21715(3-[benzyl(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384050BDBM50384050(CHEMBL2017548)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384051BDBM50384051(CHEMBL2017542)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21712BDBM21712(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21713BDBM21713(3-[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-...)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384049BDBM50384049(CHEMBL2032445)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21674BDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBile acid receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384047BDBM50384047(DEOXYCHOLIC ACID | KYBELLA)
Affinity DataEC50:  5.00E+4nMAssay Description:Agonist activity at human recombinant FXR expressed in HEK293 cells coexpressing CMX-GAL4N by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed