Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50039975
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387094BDBM50387094(CHEMBL2047224)
Affinity DataIC50: 600nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387090BDBM50387090(CHEMBL2047229)
Affinity DataIC50: 600nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387092BDBM50387092(CHEMBL2047227)
Affinity DataIC50: 700nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387088BDBM50387088(CHEMBL2047375)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387095BDBM50387095(CHEMBL2047223)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387092BDBM50387092(CHEMBL2047227)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387095BDBM50387095(CHEMBL2047223)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387091BDBM50387091(CHEMBL2047228)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387094BDBM50387094(CHEMBL2047224)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387093BDBM50387093(CHEMBL2047225)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10404BDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387093BDBM50387093(CHEMBL2047225)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387088BDBM50387088(CHEMBL2047375)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387097BDBM50387097(CHEMBL2047226)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387090BDBM50387090(CHEMBL2047229)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387089BDBM50387089(CHEMBL2047231)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387092BDBM50387092(CHEMBL2047227)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387094BDBM50387094(CHEMBL2047224)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387095BDBM50387095(CHEMBL2047223)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387093BDBM50387093(CHEMBL2047225)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387089BDBM50387089(CHEMBL2047231)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387090BDBM50387090(CHEMBL2047229)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387096BDBM50387096(CHEMBL2047230)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387097BDBM50387097(CHEMBL2047226)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387089BDBM50387089(CHEMBL2047231)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387091BDBM50387091(CHEMBL2047228)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387096BDBM50387096(CHEMBL2047230)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10404BDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of equine BuChE using butyrylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387088BDBM50387088(CHEMBL2047375)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387091BDBM50387091(CHEMBL2047228)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 5 mins by DTNB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Waterloo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387087BDBM50387087(CHEMBL2047376)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed