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Found 22 Enz. Inhib. hit(s) with all data for entry = 50040063
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of angiotensin AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388737(CHEMBL2058860)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388736(CHEMBL2058859)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388738(CHEMBL2058861)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388741(CHEMBL2058864)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataIC50:  16.2nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388732(CHEMBL2058855)
Affinity DataIC50:  19.7nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388739(CHEMBL2058862)
Affinity DataIC50:  22.5nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388730(CHEMBL2058865)
Affinity DataIC50:  37.6nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388740(CHEMBL2058863)
Affinity DataIC50:  78nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388733(CHEMBL2058856)
Affinity DataIC50:  78.3nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388735(CHEMBL2058858)
Affinity DataIC50:  96.8nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388734(CHEMBL2058857)
Affinity DataIC50:  119nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)
Affinity DataIC50:  150nMAssay Description:Inhibition of angiotensin AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388742(CHEMBL2058866)
Affinity DataIC50:  209nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388731(CHEMBL2058588)
Affinity DataIC50:  410nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388736(CHEMBL2058859)
Affinity DataKd:  4.79nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388737(CHEMBL2058860)
Affinity DataKd:  1.70nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388738(CHEMBL2058861)
Affinity DataKd:  14.8nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataKd:  12.6nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
School Of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388741(CHEMBL2058864)
Affinity DataKd:  1.82nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed