Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50040012
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387831BDBM50387831(CHEMBL2059114)
Affinity DataIC50: 19nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387833BDBM50387833(CHEMBL2058665)
Affinity DataIC50: 22nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387832BDBM50387832(CHEMBL2058906)
Affinity DataIC50: 22nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387835BDBM50387835(CHEMBL2058900)
Affinity DataIC50: 23nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387834BDBM50387834(CHEMBL2059115)
Affinity DataIC50: 23nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387837BDBM50387837(CHEMBL2058664)
Affinity DataIC50: 24nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387836BDBM50387836(CHEMBL2058905)
Affinity DataIC50: 24nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387838BDBM50387838(CHEMBL2057522)
Affinity DataIC50: 26nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387828BDBM50387828(CHEMBL2057523)
Affinity DataIC50: 26nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387839BDBM50387839(CHEMBL2057527)
Affinity DataIC50: 27nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387840BDBM50387840(CHEMBL2057518)
Affinity DataIC50: 28nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387841BDBM50387841(CHEMBL2057791)
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387842BDBM50387842(CHEMBL2057792)
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387843BDBM50387843(CHEMBL2058910)
Affinity DataIC50: 31nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387844BDBM50387844(CHEMBL2057790)
Affinity DataIC50: 31nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387845BDBM50387845(CHEMBL2059117)
Affinity DataIC50: 33nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387847BDBM50387847(CHEMBL2057788)
Affinity DataIC50: 37nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387846BDBM50387846(CHEMBL2058663)
Affinity DataIC50: 37nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387849BDBM50387849(CHEMBL2057787)
Affinity DataIC50: 38nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387848BDBM50387848(CHEMBL2059120)
Affinity DataIC50: 38nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387850BDBM50387850(CHEMBL2057786)
Affinity DataIC50: 39nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387851BDBM50387851(CHEMBL2057524)
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387852BDBM50387852(CHEMBL2057517)
Affinity DataIC50: 41nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387853BDBM50387853(CHEMBL2058901)
Affinity DataIC50: 42nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387854BDBM50387854(CHEMBL2058903)
Affinity DataIC50: 44nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387855BDBM50387855(CHEMBL2058904)
Affinity DataIC50: 52nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387856BDBM50387856(CHEMBL2059119)
Affinity DataIC50: 53nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387829BDBM50387829(CHEMBL2057528)
Affinity DataIC50: 55nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387857BDBM50387857(CHEMBL2057521)
Affinity DataIC50: 60nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387858BDBM50387858(CHEMBL2057794)
Affinity DataIC50: 69nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387859BDBM50387859(CHEMBL2057520)
Affinity DataIC50: 79nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387860BDBM50387860(CHEMBL2057514)
Affinity DataIC50: 84nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387861BDBM50387861(CHEMBL2059116)
Affinity DataIC50: 90nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387862BDBM50387862(CHEMBL2059123)
Affinity DataIC50: 92nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387863BDBM50387863(CHEMBL2057789)
Affinity DataIC50: 97nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387864BDBM50387864(CHEMBL2059126)
Affinity DataIC50: 110nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387865BDBM50387865(CHEMBL2059127)
Affinity DataIC50: 120nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387866BDBM50387866(CHEMBL2059122)
Affinity DataIC50: 130nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387867BDBM50387867(CHEMBL2058909)
Affinity DataIC50: 140nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387869BDBM50387869(CHEMBL2057525)
Affinity DataIC50: 140nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387868BDBM50387868(CHEMBL2059121)
Affinity DataIC50: 140nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387870BDBM50387870(CHEMBL2057516)
Affinity DataIC50: 180nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387871BDBM50387871(CHEMBL2058907)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387873BDBM50387873(CHEMBL2057515)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387872BDBM50387872(CHEMBL2059124)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387874BDBM50387874(CHEMBL2059125)
Affinity DataIC50: 230nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387830BDBM50387830(CHEMBL2058908)
Affinity DataIC50: 410nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen Infectious Diseases-Diagnostics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387875BDBM50387875(CHEMBL2058902)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed