Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50022642
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as reduction in phosphorylated FLT3 protein expression incubated for 3 hrs by Western bl...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged recombinant FLT3 D835Y mutant (unknown origin) expressed in baculovirus expression system using poly(Glu,Tyr) as substrate i...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of FLT3 in human RS4-11 cells assessed as reduction in phosphorylated STAT5 protein expression incubated for 3 hrs in presence of FLT3 lig...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of FLT3-ITD mutant in human MOLM-13 cells assessed as reduction in phosphorylated STAT5 protein expression incubated for 3 hrs in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-tagged recombinant FLT3 (unknown origin) expressed in baculovirus expression system using poly(Glu,Tyr) as substrate incubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-tagged recombinant JAK2 (unknown origin) expressed in baculovirus expression system using poly(Glu,Ala,Tyr) as substrate incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as reduction in phosphorylated AKT protein expression incubated for 3 hrs by Western blo...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as reduction in phosphorylated ERK1/2 protein expression incubated for 3 hrs by Western ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as reduction in phosphorylated STAT5 protein expression incubated for 3 hrs by Western b...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of GST-tagged recombinant TYK2 (unknown origin) expressed in baculovirus expression system using poly(Glu,Ala,Tyr) as substrate incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as reduction in phosphorylated FLT3 protein expression incubated for 3 hrs by Western bl...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of FLT3-ITD mutant in human MOLM-13 cells assessed as reduction in phosphorylated FLT3 protein expression incubated for 3 hrs in presence ...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of FLT3 in human derived Acute myeloid leukemic cells assessed as reduction in phosphorylated STAT3 protein expression after 3 hrs by West...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of FLT3 in human derived Acute myeloid leukemic cells assessed as reduction in phosphorylated STAT5 protein expression after 3 hrs by West...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of FLT3 in human derived Acute myeloid leukemic cells assessed as reduction in phosphorylated FLT3 protein expression after 3 hrs by Weste...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of GST-tagged recombinant JAK3 (unknown origin) expressed in baculovirus expression system using poly(Glu,Ala,Tyr) as substrate incubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of FLT3 in human RS4-11 cells assessed as reduction in phosphorylated FLT3 protein expression incubated for 3 hrs in presence of FLT3 liga...More data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 (866 to 1154 residues) expressed in insect cells using poly(Glu,Ala,Tyr) as substrate incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of JAK in human linifanib-resistant MV4-11 cells harboring FLT3-ITD mutant assessed as reduction in cell viability incubated for 48 hr by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of JAK in human MV4-11 cells harboring FLT3-ITD mutant assessed as reduction in cell viability incubated for 48 hr by CellTiter-Glo assayMore data for this Ligand-Target Pair
