Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50042130
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421140BDBM50421140(CHEMBL2088591)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421137BDBM50421137(CHEMBL2088588)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421141BDBM50421141(CHEMBL2088578)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421127BDBM50421127(CHEMBL2088582)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421139BDBM50421139(CHEMBL2088590)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421138BDBM50421138(CHEMBL2088589)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421128BDBM50421128(CHEMBL2088583)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421133BDBM50421133(CHEMBL2088575)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421132BDBM50421132(CHEMBL2088579)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421125BDBM50421125(CHEMBL2088586)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421134BDBM50421134(CHEMBL2088576)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317579BDBM50317579(6-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)-2H-q...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421141BDBM50421141(CHEMBL2088578)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421140BDBM50421140(CHEMBL2088591)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421136BDBM50421136(CHEMBL2088587)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421130BDBM50421130(CHEMBL2088580)
Affinity DataIC50: 9nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317579BDBM50317579(6-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)-2H-q...)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421137BDBM50421137(CHEMBL2088588)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421135BDBM50421135(CHEMBL2088577)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317588BDBM50317588(6-(2,4-difluorophenyl)-1-(2-fluoro-5-(5-methyl-1,3...)
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317583BDBM50317583(1-(2,6-difluoro-4-(5-methyl-1,3,4-oxadiazol-2-yl)p...)
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317588BDBM50317588(6-(2,4-difluorophenyl)-1-(2-fluoro-5-(5-methyl-1,3...)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317583BDBM50317583(1-(2,6-difluoro-4-(5-methyl-1,3,4-oxadiazol-2-yl)p...)
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421126BDBM50421126(CHEMBL2088585)
Affinity DataIC50: 17nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421127BDBM50421127(CHEMBL2088582)
Affinity DataIC50: 27nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421129BDBM50421129(CHEMBL2088584)
Affinity DataIC50: 32nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421133BDBM50421133(CHEMBL2088575)
Affinity DataIC50: 36nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421132BDBM50421132(CHEMBL2088579)
Affinity DataIC50: 53.5nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421139BDBM50421139(CHEMBL2088590)
Affinity DataIC50: 64nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421128BDBM50421128(CHEMBL2088583)
Affinity DataIC50: 66nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421125BDBM50421125(CHEMBL2088586)
Affinity DataIC50: 86nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421131BDBM50421131(CHEMBL2088581)
Affinity DataIC50: 99nMAssay Description:Inhibition of mouse p38apha assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421138BDBM50421138(CHEMBL2088589)
Affinity DataIC50: 110nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421136BDBM50421136(CHEMBL2088587)
Affinity DataIC50: 140nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421134BDBM50421134(CHEMBL2088576)
Affinity DataIC50: 180nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421130BDBM50421130(CHEMBL2088580)
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421135BDBM50421135(CHEMBL2088577)
Affinity DataIC50: 230nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421126BDBM50421126(CHEMBL2088585)
Affinity DataIC50: 300nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421129BDBM50421129(CHEMBL2088584)
Affinity DataIC50: 400nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421131BDBM50421131(CHEMBL2088581)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse p38beta assessed as reduction in GST-ATF2 substrate phosphorylation by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317579BDBM50317579(6-(2,4-difluorophenyl)-1-(2,6-difluorophenyl)-2H-q...)
Affinity DataEC50:  3.30E+3nMAssay Description:Activation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421125BDBM50421125(CHEMBL2088586)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317588BDBM50317588(6-(2,4-difluorophenyl)-1-(2-fluoro-5-(5-methyl-1,3...)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317583BDBM50317583(1-(2,6-difluoro-4-(5-methyl-1,3,4-oxadiazol-2-yl)p...)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed