Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 50040765
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 10nMAssay Description:Inhibition of DGAT1 in human HuTu80 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 10nMAssay Description:Inhibition of DGAT1 in human HuTu80 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399678BDBM50399678(CHEMBL2178369)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399681BDBM50399681(CHEMBL2178947)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399685BDBM50399685(CHEMBL2178943)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399715BDBM50399715(CHEMBL2178373)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399686BDBM50399686(CHEMBL2178942)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 60nMAssay Description:Inhibition of DGAT1 in dog liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399688BDBM50399688(CHEMBL2178940)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 70nMAssay Description:Inhibition of DGAT1 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399682BDBM50399682(CHEMBL2178946)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399714BDBM50399714(CHEMBL2178371)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 90nMAssay Description:Inhibition of DGAT1 in rat adipose tissue assessed as reduction in triacylglycerol synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 100nMAssay Description:Inhibition of DGAT1 in mouse liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399689BDBM50399689(CHEMBL2178939)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399691BDBM50399691(CHEMBL2178937)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399707BDBM50399707(CHEMBL2178384)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399677BDBM50399677(CHEMBL2178370)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399683BDBM50399683(CHEMBL2178945)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399687BDBM50399687(CHEMBL2178941)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 150nMAssay Description:Inhibition of DGAT1 in rat adipose tissue assessed as reduction in triacylglycerol synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399680BDBM50399680(CHEMBL2178948)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399716BDBM50399716(CHEMBL2178372)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399679BDBM50399679(CHEMBL2178949)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399712BDBM50399712(CHEMBL2178951)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399703BDBM50399703(CHEMBL2178388)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399684BDBM50399684(CHEMBL2178944)
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399693BDBM50399693(CHEMBL2178935)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399709BDBM50399709(CHEMBL2178954)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399695BDBM50399695(CHEMBL2178933)
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399690BDBM50399690(CHEMBL2178938)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399713BDBM50399713(CHEMBL2178950)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399694BDBM50399694(CHEMBL2178934)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399702BDBM50399702(CHEMBL2178389)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399692BDBM50399692(CHEMBL2178936)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399711BDBM50399711(CHEMBL2178952)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399681BDBM50399681(CHEMBL2178947)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human ACAT1 by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of PDE10A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399698BDBM50399698(CHEMBL2178930)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ACAT2 by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399697BDBM50399697(CHEMBL2178931)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399696BDBM50399696(CHEMBL2178932)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399699BDBM50399699(CHEMBL2178392)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399701BDBM50399701(CHEMBL2178390)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399700BDBM50399700(CHEMBL2178391)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399714BDBM50399714(CHEMBL2178371)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ACAT1 by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399707BDBM50399707(CHEMBL2178384)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human ACAT1 by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399693BDBM50399693(CHEMBL2178935)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human ACAT1 by liquid scintillographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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