Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 8293
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  370nM ΔG°:  -36.7kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239178(Thiazolidin-based CA inhibitor, 6b | (2S,5R)-5-met...)
Affinity DataKi:  810nM ΔG°:  -34.8kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239177(Thiazolidin-based CA inhibitor, 6a | (2S,5S)-5-met...)
Affinity DataKi:  930nM ΔG°:  -34.4kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239174(Thiazolidin-based CA inhibitor, 4)
Affinity DataKi:  1.32E+3nM ΔG°:  -33.6kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239171(Thiazolidin-based CA inhibitor, 1)
Affinity DataKi:  1.34E+3nM ΔG°:  -33.5kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239173(Thiazolidin-based CA inhibitor, 3)
Affinity DataKi:  1.36E+3nM ΔG°:  -33.5kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239175(Thiazolidin-based CA inhibitor, 5a)
Affinity DataKi:  2.29E+3nM ΔG°:  -32.2kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239172(Thiazolidin-based CA inhibitor, 2)
Affinity DataKi:  2.48E+3nM ΔG°:  -32.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239176(Thiazolidin-based CA inhibitor, 5b)
Affinity DataKi:  3.59E+3nM ΔG°:  -31.1kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239178(Thiazolidin-based CA inhibitor, 6b | (2S,5R)-5-met...)
Affinity DataKi:  4.43E+3nM ΔG°:  -30.6kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239173(Thiazolidin-based CA inhibitor, 3)
Affinity DataKi:  5.38E+3nM ΔG°:  -30.1kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239174(Thiazolidin-based CA inhibitor, 4)
Affinity DataKi:  5.51E+3nM ΔG°:  -30.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239177(Thiazolidin-based CA inhibitor, 6a | (2S,5S)-5-met...)
Affinity DataKi:  5.58E+3nM ΔG°:  -30.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239171(Thiazolidin-based CA inhibitor, 1)
Affinity DataKi:  6.80E+3nM ΔG°:  -29.5kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239175(Thiazolidin-based CA inhibitor, 5a)
Affinity DataKi:  2.75E+4nM ΔG°:  -26.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239176(Thiazolidin-based CA inhibitor, 5b)
Affinity DataKi:  2.94E+4nM ΔG°:  -25.9kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  3.62E+4nM ΔG°:  -25.3kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239172(Thiazolidin-based CA inhibitor, 2)
Affinity DataKi:  4.75E+4nM ΔG°:  -24.7kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed