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Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50042479
TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426601(CHEMBL2325895)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426599(CHEMBL2325898)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426607(CHEMBL2325897)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426599(CHEMBL2325898)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426599(CHEMBL2325898)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426601(CHEMBL2325895)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426606(CHEMBL2325903)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426604(CHEMBL2325906)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426601(CHEMBL2325895)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426616(CHEMBL2325899)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426602(CHEMBL2325894)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426615(CHEMBL2325900)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426603(CHEMBL2325912)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426617(CHEMBL2325902)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426604(CHEMBL2325906)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426606(CHEMBL2325903)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426605(CHEMBL2325904)
Affinity DataIC50:  17nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426614(CHEMBL2325905)
Affinity DataIC50:  19nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426615(CHEMBL2325900)
Affinity DataIC50:  22nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426603(CHEMBL2325912)
Affinity DataIC50:  23nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426615(CHEMBL2325900)
Affinity DataIC50:  24nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426616(CHEMBL2325899)
Affinity DataIC50:  33nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426602(CHEMBL2325894)
Affinity DataIC50:  37nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426614(CHEMBL2325905)
Affinity DataIC50:  43nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426617(CHEMBL2325902)
Affinity DataIC50:  44nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426613(CHEMBL2325907)
Affinity DataIC50:  44nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426618(CHEMBL2325901)
Affinity DataIC50:  45nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426603(CHEMBL2325912)
Affinity DataIC50:  45nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426606(CHEMBL2325903)
Affinity DataIC50:  45nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426616(CHEMBL2325899)
Affinity DataIC50:  45nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426602(CHEMBL2325894)
Affinity DataIC50:  47nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426610(CHEMBL2325910)
Affinity DataIC50:  49nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426611(CHEMBL2325909)
Affinity DataIC50:  69nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426617(CHEMBL2325902)
Affinity DataIC50:  76nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426605(CHEMBL2325904)
Affinity DataIC50:  77nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426608(CHEMBL2325913)
Affinity DataIC50:  81nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426614(CHEMBL2325905)
Affinity DataIC50:  100nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426612(CHEMBL2325908)
Affinity DataIC50:  104nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426618(CHEMBL2325901)
Affinity DataIC50:  106nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426604(CHEMBL2325906)
Affinity DataIC50:  108nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426610(CHEMBL2325910)
Affinity DataIC50:  122nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426611(CHEMBL2325909)
Affinity DataIC50:  123nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426608(CHEMBL2325913)
Affinity DataIC50:  134nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426609(CHEMBL2325911)
Affinity DataIC50:  148nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  184nMAssay Description:Inhibition of JAK2 in human PBMC expressing CD14 assessed as inhibition of GM-CSF-stimulated STAT5a phosphorylation after 30 mins by flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426601(CHEMBL2325895)
Affinity DataIC50:  188nMAssay Description:Inhibition of JAK2 in human PBMC expressing CD14 assessed as inhibition of GM-CSF-stimulated STAT5a phosphorylation after 30 mins by flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase JAK2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426600(CHEMBL2325896)
Affinity DataIC50:  206nMAssay Description:Inhibition of JAK2 in human PBMC expressing CD14 assessed as inhibition of GM-CSF-stimulated STAT5a phosphorylation after 30 mins by flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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