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Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50042411
TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425681(CHEMBL2315564)
Affinity DataIC50:  37nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425672(CHEMBL2315584)
Affinity DataIC50:  37nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425687(CHEMBL2315565)
Affinity DataIC50:  45nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425686(CHEMBL2315566)
Affinity DataIC50:  45nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425679(CHEMBL2315562)
Affinity DataIC50:  51nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425688(CHEMBL2315563)
Affinity DataIC50:  57nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425687(CHEMBL2315565)
Affinity DataIC50:  83nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425686(CHEMBL2315566)
Affinity DataIC50:  107nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425685(CHEMBL2315572)
Affinity DataIC50:  130nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425684(CHEMBL2315571)
Affinity DataIC50:  170nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425673(CHEMBL2315580)
Affinity DataIC50:  177nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425675(CHEMBL2315579)
Affinity DataIC50:  195nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425667(CHEMBL2315583)
Affinity DataIC50:  220nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425681(CHEMBL2315564)
Affinity DataIC50:  365nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425679(CHEMBL2315562)
Affinity DataIC50:  552nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425678(CHEMBL2315567)
Affinity DataIC50:  640nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425677(CHEMBL2315573)
Affinity DataIC50:  700nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425676(CHEMBL2315577)
Affinity DataIC50:  910nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425675(CHEMBL2315579)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425673(CHEMBL2315580)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425672(CHEMBL2315584)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425671(CHEMBL2315578)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425670(CHEMBL2315561)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425668(CHEMBL2315576)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425667(CHEMBL2315583)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425666(CHEMBL2315575)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425664(CHEMBL2315559)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425670(CHEMBL2315561)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425677(CHEMBL2315573)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425684(CHEMBL2315571)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425689(CHEMBL2315570)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425683(CHEMBL2315569)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425674(CHEMBL2315568)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425680(CHEMBL2315582)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425682(CHEMBL2315581)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425669(CHEMBL2315574)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425685(CHEMBL2315572)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425688(CHEMBL2315563)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425671(CHEMBL2315578)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425676(CHEMBL2315577)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425668(CHEMBL2315576)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425666(CHEMBL2315575)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425663(CHEMBL2315558)
Affinity DataKd:  5.70E+4nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425686(CHEMBL2315566)
Affinity DataKd:  9nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425665(CHEMBL2315560)
Affinity DataKd:  4.30E+4nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425668(CHEMBL2315576)
Affinity DataKd:  6.38E+3nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425669(CHEMBL2315574)
Affinity DataKd:  4.76E+3nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425666(CHEMBL2315575)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425674(CHEMBL2315568)
Affinity DataKd:  1.13E+3nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFocal adhesion kinase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50425673(CHEMBL2315580)
Affinity DataKd:  603nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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