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Found 6 Enz. Inhib. hit(s) with all data for entry = 50042425
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425908(CHEMBL2313363)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425909(SPIRUCHOSTATIN C)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425908(CHEMBL2313363)
Affinity DataIC50:  240nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425909(SPIRUCHOSTATIN C)
Affinity DataIC50:  320nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  390nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed