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Report error Found 80 Enz. Inhib. hit(s) with all data for entry = 50042694
TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  2nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  2nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  3nMT: 25°CAssay Description:Inhibition of HDAC3 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429531(CHEMBL2333340)
Affinity DataIC50:  4nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  4nMT: 25°CAssay Description:Inhibition of HDAC1 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429530(CHEMBL2333341)
Affinity DataIC50:  7nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429532(CHEMBL2333339)
Affinity DataIC50:  8nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  11nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429527(CHEMBL2333344)
Affinity DataIC50:  12nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015088((E)-N-Hydroxy-3-phenyl-acrylamide | (E)-N-Hydroxy-...)
Affinity DataIC50:  22nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429528(CHEMBL2333343)
Affinity DataIC50:  28nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429525(CHEMBL2333346)
Affinity DataIC50:  30nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429529(CHEMBL2333342)
Affinity DataIC50:  37nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015184(BENZHYDROXAMIC ACID | BENZOHYDROXAMATE | CHEMBL163...)
Affinity DataIC50:  115nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  144nMT: 25°CAssay Description:Inhibition of HDAC1 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  155nMT: 25°CAssay Description:Inhibition of HDAC3 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429529(CHEMBL2333342)
Affinity DataIC50:  321nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429532(CHEMBL2333339)
Affinity DataIC50:  341nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  360nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429526(CHEMBL2333345 | N-Hydroxycyclohexanecarboxamide)
Affinity DataIC50:  376nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 7(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  379nMT: 25°CAssay Description:Inhibition of HDAC7 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429530(CHEMBL2333341)
Affinity DataIC50:  381nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429527(CHEMBL2333344)
Affinity DataIC50:  431nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015112(CHEMBL152162 | N-Hydroxy-3-phenyl-propionamide | N...)
Affinity DataIC50:  448nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015088((E)-N-Hydroxy-3-phenyl-acrylamide | (E)-N-Hydroxy-...)
Affinity DataIC50:  457nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429531(CHEMBL2333340)
Affinity DataIC50:  607nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 9(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  621nMT: 25°CAssay Description:Inhibition of HDAC9 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429525(CHEMBL2333346)
Affinity DataIC50:  638nMT: 25°CAssay Description:Inhibition of HDAC1 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  681nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429529(CHEMBL2333342)
Affinity DataIC50:  689nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429525(CHEMBL2333346)
Affinity DataIC50:  694nMT: 25°CAssay Description:Inhibition of HDAC3 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015088((E)-N-Hydroxy-3-phenyl-acrylamide | (E)-N-Hydroxy-...)
Affinity DataIC50:  759nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.02E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429530(CHEMBL2333341)
Affinity DataIC50:  1.03E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429527(CHEMBL2333344)
Affinity DataIC50:  1.05E+3nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429525(CHEMBL2333346)
Affinity DataIC50:  1.09E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 4(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  1.10E+3nMT: 25°CAssay Description:Inhibition of HDAC4 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015094(CHEMBL152665 | N-Hydroxy-2-phenyl-acetamide | N-hy...)
Affinity DataIC50:  1.10E+3nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429531(CHEMBL2333340)
Affinity DataIC50:  1.15E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429532(CHEMBL2333339)
Affinity DataIC50:  1.33E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429533(CHEMBL2333338)
Affinity DataIC50:  1.36E+3nMT: 25°CAssay Description:Inhibition of HDAC6 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429528(CHEMBL2333343)
Affinity DataIC50:  1.61E+3nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429525(CHEMBL2333346)
Affinity DataIC50:  1.79E+3nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015184(BENZHYDROXAMIC ACID | BENZOHYDROXAMATE | CHEMBL163...)
Affinity DataIC50:  1.92E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429528(CHEMBL2333343)
Affinity DataIC50:  1.95E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 5(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  2.30E+3nMT: 25°CAssay Description:Inhibition of HDAC5 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015112(CHEMBL152162 | N-Hydroxy-3-phenyl-propionamide | N...)
Affinity DataIC50:  2.35E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015112(CHEMBL152162 | N-Hydroxy-3-phenyl-propionamide | N...)
Affinity DataIC50:  2.72E+3nMT: 25°CAssay Description:Inhibition of HDAC2 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50429526(CHEMBL2333345 | N-Hydroxycyclohexanecarboxamide)
Affinity DataIC50:  3.72E+3nMT: 25°CAssay Description:Inhibition of HDAC8 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50015184(BENZHYDROXAMIC ACID | BENZOHYDROXAMATE | CHEMBL163...)
Affinity DataIC50:  4.73E+3nMT: 25°CAssay Description:Inhibition of HDAC1 (unknown origin) assessed as fluorescence intensity measured after 60 mins incubation at room temperature by trypsin-free microfl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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