Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50045949
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50088512(CHEBI:59609 | CHEMBL3527338)
Affinity DataKi:  4.32E+3nMAssay Description:Reversible inhibition of human CES1 assessed as hydrolysis of 4NPA to 4NPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50088513(CHEMBL3526940)
Affinity DataKi:  2.48E+4nMAssay Description:Reversible inhibition of human CES1 assessed as hydrolysis of 4NPA to 4NPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50088514(CHEBI:88735 | CHEMBL3526740)
Affinity DataKi:  3.55E+5nMAssay Description:Reversible inhibition of human CES1 assessed as hydrolysis of 4NPA to 4NPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataKi:  3.63E+5nMAssay Description:Inhibition of human CES1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50088516(CHEMBL3526990)
Affinity DataKi:  4.68E+5nMAssay Description:Reversible inhibition of human CES1 assessed as hydrolysis of 4NPA to 4NPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50088515(CHEMBL3526991)
Affinity DataKi:  7.07E+5nMAssay Description:Reversible inhibition of human CES1 assessed as hydrolysis of 4NPA to 4NPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataKi:  7.90E+6nMAssay Description:Inhibition of human CES2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50088512(CHEBI:59609 | CHEMBL3527338)
Affinity DataIC50:  1.96E+3nMAssay Description:Time-dependent inhibition of human CES1 assessed as hydrolysis of 4NPA to 4NP preincubated for 30 mins followed by 4NPA additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50088512(CHEBI:59609 | CHEMBL3527338)
Affinity DataIC50:  2.27E+3nMAssay Description:Time-dependent inhibition of human CES1 assessed as hydrolysis of 4NPA to 4NP preincubated for 60 mins followed by 4NPA additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50088512(CHEBI:59609 | CHEMBL3527338)
Affinity DataIC50:  2.51E+3nMAssay Description:Time-dependent inhibition of human CES1 assessed as hydrolysis of 4NPA to 4NP preincubated for 10 mins followed by 4NPA additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed