Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50042825
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431696(CHEMBL2349534)
Affinity DataIC50: 1.10nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431690(CHEMBL2349540)
Affinity DataIC50: 2.30nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431692(CHEMBL2349538)
Affinity DataIC50: 3.70nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431695(CHEMBL2349535)
Affinity DataIC50: 3.80nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431693(CHEMBL2349537)
Affinity DataIC50: 4.30nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431697(CHEMBL2349533)
Affinity DataIC50: 4.40nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431694(CHEMBL2349536)
Affinity DataIC50: 4.70nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431691(CHEMBL2349539)
Affinity DataIC50: 5.30nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431689(CHEMBL2349541)
Affinity DataIC50: 5.30nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431717(CHEMBL2346726)
Affinity DataIC50: 5.80nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431722(CHEMBL2346721)
Affinity DataIC50: 7.10nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431728(CHEMBL2346715)
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431719(MTE | CHEMBL2346724)
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50122758(3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...)
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431718(CHEMBL2346725)
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431716(CHEMBL2346727)
Affinity DataIC50: 15nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431721(CHEMBL2346722)
Affinity DataIC50: 16nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431678(CHEMBL2346711)
Affinity DataIC50: 16nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431687(CHEMBL2349543)
Affinity DataIC50: 17nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431713(CHEMBL2346730)
Affinity DataIC50: 17nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431705(ADX48621 | Dipraglurant | CHEMBL2346738)
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431712(CHEMBL2346731)
Affinity DataIC50: 24nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431684(CHEMBL2349546)
Affinity DataIC50: 25nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431704(CHEMBL2346739)
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431701(CHEMBL2349529)
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431730(CHEMBL2346713)
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431688(CHEMBL2349542)
Affinity DataIC50: 38nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431706(CHEMBL2346737)
Affinity DataIC50: 40nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431723(CHEMBL2346720)
Affinity DataIC50: 42nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431714(CHEMBL2346729)
Affinity DataIC50: 46nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431724(CHEMBL2346719)
Affinity DataIC50: 56nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431708(CHEMBL2346735)
Affinity DataIC50: 62nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431702(CHEMBL2349528)
Affinity DataIC50: 63nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431685(CHEMBL2349545)
Affinity DataIC50: 71nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431710(CHEMBL2346733)
Affinity DataIC50: 77nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431679(CHEMBL2349553)
Affinity DataIC50: 82nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431707(CHEMBL2346736)
Affinity DataIC50: 88nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431680(CHEMBL2349552)
Affinity DataIC50: 91nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431683(CHEMBL2349547)
Affinity DataIC50: 92nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431725(CHEMBL2346718)
Affinity DataIC50: 95nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431698(CHEMBL2349532)
Affinity DataIC50: 95nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431677(CHEMBL2346712)
Affinity DataIC50: 130nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431709(CHEMBL2346734)
Affinity DataIC50: 139nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431715(CHEMBL2346728)
Affinity DataIC50: 147nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431711(CHEMBL2346732)
Affinity DataIC50: 173nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431727(CHEMBL2346716)
Affinity DataIC50: 184nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431729(CHEMBL2346714)
Affinity DataIC50: 195nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431726(CHEMBL2346717)
Affinity DataIC50: 301nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431703(CHEMBL2349527)
Affinity DataIC50: 373nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431686(CHEMBL2349544)
Affinity DataIC50: 645nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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