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Found 4 Enz. Inhib. hit(s) with all data for entry = 50043057
TargetAminopeptidase N(Sus scrofa (Pig))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50435266(CHEMBL2393088)
Affinity DataIC50:  850nMAssay Description:Inhibition of pig kidney APN using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50435266(CHEMBL2393088)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of APN in human ES-2 cells using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of pig kidney APN using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by UV-Vi...More data for this Ligand-Target Pair
TargetAminopeptidase N(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of APN in human ES-2 cells using L-Leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after 1 hr by...More data for this Ligand-Target Pair