Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50005344
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491275BDBM50491275(CHEMBL2381680)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491266BDBM50491266(CHEMBL2381677)
Affinity DataIC50: 3.08E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491270BDBM50491270(CHEMBL2381578)
Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491261BDBM50491261(CHEMBL2381580)
Affinity DataIC50: 4.75E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491271BDBM50491271(CHEMBL2381676)
Affinity DataIC50: 7.24E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491262BDBM50491262(CHEMBL2381579)
Affinity DataIC50: 7.49E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491260BDBM50491260(CHEMBL2381678)
Affinity DataIC50: 8.49E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491267BDBM50491267(CHEMBL2381576)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491276BDBM50491276(CHEMBL2381573)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491268BDBM50491268(CHEMBL2381577)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491269BDBM50491269(CHEMBL2381675)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491264BDBM50491264(CHEMBL2381682)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491263BDBM50491263(CHEMBL2381574)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491265BDBM50491265(CHEMBL2381681)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491259BDBM50491259(CHEMBL2381679)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491272BDBM50491272(CHEMBL2381575)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491274BDBM50491274(CHEMBL2381572)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Shionogi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491273BDBM50491273(CHEMBL2381581)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed