Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 6038
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105212(2-(4-Nonyl-piperazin-1-yl)-6-nitroquinoline (9))
Affinity DataKi:  1.80nM ΔG°:  -49.9kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105213(2-(4-Decyl-piperazin-1-yl)-6-nitroquinoline (10))
Affinity DataKi:  4.5nM ΔG°:  -47.6kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105214(2-(4-Undecyl-piperazin-1-yl)-6-nitroquinoline (11))
Affinity DataKi:  12.6nM ΔG°:  -45.1kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105215(2-(4-Dodecyl-piperazin-1-yl)-6-nitroquinoline (12))
Affinity DataKi:  16.1nM ΔG°:  -44.5kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105211(2-(4-Octyl-piperazin-1-yl)-6-nitroquinoline (8))
Affinity DataKi:  20.8nM ΔG°:  -43.8kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105207(2-(4-Butyl-piperazin-1-yl)-6-nitroquinoline (4))
Affinity DataKi:  24nM ΔG°:  -43.5kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105210(2-(4-Heptyl-piperazin-1-yl)-6-nitroquinoline (7))
Affinity DataKi:  54.1nM ΔG°:  -41.5kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105209(2-(4-Hexyl-piperazin-1-yl)-6-nitroquinoline (6))
Affinity DataKi:  72.9nM ΔG°:  -40.7kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105208(2-(4-Pentyl-piperazin-1-yl)-6-nitroquinoline (5))
Affinity DataKi:  80.5nM ΔG°:  -40.5kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105205(2-(4-Ethyl-piperazin-1-yl)-6-nitroquinoline (2))
Affinity DataKi:  86.1nM ΔG°:  -40.3kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105206(2-(4-Propyl-piperazin-1-yl)-6-nitroquinoline (3))
Affinity DataKi:  496nM ΔG°:  -36.0kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Troms£

LigandPNGBDBM105204(2-(4-Methyl-piperazin-1-yl)-6-nitroquinoline (1))
Affinity DataKi:  1.30E+3nM ΔG°:  -33.6kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed