Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50043066
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10246BDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435417BDBM50435417(CHEMBL2391912)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435416BDBM50435416(CHEMBL2391780)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435415BDBM50435415(CHEMBL2391779)
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 61946BDBM61946(KUC105339N | 3-oxidanylidene-N-phenyl-1,2-benzothi...)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435414BDBM50435414(CHEMBL2391777)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 61945BDBM61945(N-benzyl-3-oxo-1,2-benzothiazole-2-carboxamide | K...)
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435413BDBM50435413(CHEMBL2391778)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435412BDBM50435412(CHEMBL2391911)
Affinity DataIC50: 115nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435411BDBM50435411(CHEMBL2391781)
Affinity DataIC50: 206nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435410BDBM50435410(CHEMBL2391910)
Affinity DataIC50: 241nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435409BDBM50435409(CHEMBL2391772)
Affinity DataIC50: 438nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34737BDBM34737(2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...)
Affinity DataIC50: 466nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 44439BDBM44439(MLS000042133 | SMR000048426 | 2-[3-(1-pyrrolidinyl...)
Affinity DataIC50: 533nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435408BDBM50435408(CHEMBL2391773)
Affinity DataIC50: 593nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435407BDBM50435407(CHEMBL2391918)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435406BDBM50435406(CHEMBL2391922)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435405BDBM50435405(CHEMBL2391917)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435404BDBM50435404(CHEMBL2391920)
Affinity DataIC50: 8.09E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435403BDBM50435403(CHEMBL2391921)
Affinity DataIC50: 9.63E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435402BDBM50435402(CHEMBL2391774)
Affinity DataIC50: 9.82E+3nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435401BDBM50435401(CHEMBL2391919)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435400BDBM50435400(CHEMBL99313 | acs.jmedchem.1c00409_ST.173)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435399BDBM50435399(CHEMBL2391914)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435398BDBM50435398(CHEMBL2391915)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435397BDBM50435397(CHEMBL2391923)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435396BDBM50435396(CHEMBL2391916)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435395BDBM50435395(CHEMBL2391776)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435394BDBM50435394(CHEMBL2391913 | acs.jmedchem.1c00409_ST.171)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 61908BDBM61908(KUC103657N | cid_351236 | 2-methyl-1,2-benzothiazo...)
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46658BDBM46658(MLS-0254244.0001 | cid_17520 | 1,2-benzothiazol-3-...)
Affinity DataIC50: 4.67E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435393BDBM50435393(CHEMBL1996492)
Affinity DataIC50: 9.12E+4nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCaspase-3(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435392BDBM50435392(CHEMBL2391775)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human caspase-3 using Ac-LDEVD-AMC as substrate assessed as accumulation of 7-AMC incubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed