Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50043220
TargetPlatelet-derived growth factor receptor beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50432398(CHEMBL2348996)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437508(CHEMBL2409779)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437507(CHEMBL2409781)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437505(CHEMBL2409778)
Affinity DataIC50: 12nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using biotinylated poly-GluTyr as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437505(CHEMBL2409778)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437509(CHEMBL2409775)
Affinity DataIC50: 19nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437506(CHEMBL2409790)
Affinity DataIC50: 21nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437509(CHEMBL2409775)
Affinity DataIC50: 120nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437508(CHEMBL2409779)
Affinity DataIC50: 170nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437509(CHEMBL2409775)
Affinity DataIC50: 290nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50432398(CHEMBL2348996)
Affinity DataIC50: 360nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437506(CHEMBL2409790)
Affinity DataIC50: 680nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437508(CHEMBL2409779)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437507(CHEMBL2409781)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437506(CHEMBL2409790)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437507(CHEMBL2409781)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50432398(CHEMBL2348996)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437505(CHEMBL2409778)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437505(CHEMBL2409778)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437505(CHEMBL2409778)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IR (unknown origin) using biotinylated poly-GluTyr as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437505(CHEMBL2409778)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437505(CHEMBL2409778)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1-R (unknown origin) using biotinylated poly-GluTyr as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50437505(CHEMBL2409778)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant FAK (unknown origin) expressed in baculovirus expression system using biotinylated poly-GluTyr as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed