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Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50043376
TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440120(CHEMBL1393516 | US11634391, Compound 156)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440134(CHEMBL2426244)
Affinity DataKd:  210nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440122(CHEMBL2426235)
Affinity DataEC50:  5.78E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440123(CHEMBL2426234)
Affinity DataEC50:  4.65E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440124(CHEMBL2426232)
Affinity DataEC50:  3.85E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in pqs gene-deficient Pseudomonas aeruginosa PA14 by beta-galactosidase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440125(CHEMBL2426228)
Affinity DataEC50:  2.67E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440126(CHEMBL2426233)
Affinity DataEC50:  1.78E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440127(CHEMBL2426238)
Affinity DataKd:  1.29E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440122(CHEMBL2426235)
Affinity DataKd:  1.24E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440128(CHEMBL1545380)
Affinity DataKd:  1.07E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM98803(EN300-42473 | US8487093, 193)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440128(CHEMBL1545380)
Affinity DataKd:  8.50E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50106197(3-Bromo-benzamide | CHEMBL122690)
Affinity DataKd:  7.60E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440124(CHEMBL2426232)
Affinity DataEC50:  7.50E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440129(CHEMBL2426231)
Affinity DataEC50:  7.50E+3nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM98803(EN300-42473 | US8487093, 193)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50106197(3-Bromo-benzamide | CHEMBL122690)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440121(CHEMBL2426237 | US11634391, Compound 117)
Affinity DataKd:  6.50E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440130(CHEMBL1383520 | US11634391, Compound 168)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440130(CHEMBL1383520 | US11634391, Compound 168)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440131(CHEMBL2426236)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440132(CHEMBL154085 | Naphthalene-2-Carboxylic Acid Amide)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440124(CHEMBL2426232)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440133(CHEMBL2426225)
Affinity DataKd:  900nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440132(CHEMBL154085 | Naphthalene-2-Carboxylic Acid Amide)
Affinity DataKd:  800nMAssay Description:Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVirulence factor transcriptional regulator MvfR(Pseudomonas aeruginosa)
Helmholtz-Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50440121(CHEMBL2426237 | US11634391, Compound 117)
Affinity DataEC50:  1.01E+5nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed