Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50043434
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataKi:  680nMAssay Description:Reversible inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataKi:  740nMAssay Description:Reversible inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataKi:  980nMAssay Description:Competitive inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol by Lineweave...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211({[17-(diphosphonomethyl)-26,28-dihydroxy-25,27-dip...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211({[17-(diphosphonomethyl)-26,28-dihydroxy-25,27-dip...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211({[17-(diphosphonomethyl)-26,28-dihydroxy-25,27-dip...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211({[17-(diphosphonomethyl)-26,28-dihydroxy-25,27-dip...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CD45 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441104(CHEMBL2430578)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441104(CHEMBL2430578)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CD45 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441104(CHEMBL2430578)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441104(CHEMBL2430578)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PTPbeta (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PTPbeta (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PTPbeta (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211({[17-(diphosphonomethyl)-26,28-dihydroxy-25,27-dip...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of CD45 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441104(CHEMBL2430578)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211({[17-(diphosphonomethyl)-26,28-dihydroxy-25,27-dip...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PTPbeta (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441104(CHEMBL2430578)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of CD45 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441104(CHEMBL2430578)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LAR (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LAR (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211({[17-(diphosphonomethyl)-26,28-dihydroxy-25,27-dip...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LAR (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed