Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50043441 Sort by
LigandPNGBDBM50441212(CHEMBL2431028)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441213(CHEMBL2431027)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of ADAM-17 in human SKOV3 cells transfected with luciferase gene assessed as inhibition of pervanadate-induced sALCAM release incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441228(CHEMBL2431029)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of ADAM-17 in human A2774 cells assessed as inhibition of pervanadate-induced sALCAM release incubated for 30 mins prior to pervanadate in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441214(CHEMBL2431026)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441212(CHEMBL2431028)
Affinity DataIC50: 45nMAssay Description:Inhibition of ADAM-17 in human A2774 cells assessed as inhibition of pervanadate-induced sALCAM release incubated for 30 mins prior to pervanadate in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441212(CHEMBL2431028)
Affinity DataIC50: 58nMAssay Description:Inhibition of ADAM-17 in human SKOV3 cells transfected with luciferase gene assessed as inhibition of pervanadate-induced sALCAM release incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441223(CHEMBL2431016)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441221(CHEMBL2431018)
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441219(CHEMBL2431020)
Affinity DataIC50: 82nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441224(CHEMBL2431015)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441215(CHEMBL2431021)
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441227(CHEMBL2431030)
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441212(CHEMBL2431028)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human ADAM-10 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 1 hr measured every 15 secs for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441218(CHEMBL2431022)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441226(CHEMBL2431031)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441213(CHEMBL2431027)
Affinity DataIC50: 274nMAssay Description:Inhibition of ADAM-17 in human A2774 cells assessed as inhibition of pervanadate-induced sALCAM release incubated for 30 mins prior to pervanadate in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441222(CHEMBL2431017)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441213(CHEMBL2431027)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human ADAM-10 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 1 hr measured every 15 secs for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50429818(CHEMBL2337691)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441217(CHEMBL2431024)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441213(CHEMBL2431027)
Affinity DataIC50: 349nMAssay Description:Inhibition of ADAM-17 in human A2780 cells assessed as inhibition of pervanadate-induced sALCAM release incubated for 30 mins prior to pervanadate in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441213(CHEMBL2431027)
Affinity DataIC50: 350nMAssay Description:Inhibition of ADAM-17 in human SKOV3 cells transfected with luciferase gene assessed as inhibition of pervanadate-induced sALCAM release incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)
Affinity DataIC50: 419nMAssay Description:Inhibition of ADAM-17 in human A2774 cells assessed as inhibition of EGF-induced sALCAM release incubated for 30 mins prior to EGF induction measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441216(CHEMBL2431025)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50429818(CHEMBL2337691)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441227(CHEMBL2431030)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441228(CHEMBL2431029)
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441225(CHEMBL2431032)
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441220(CHEMBL2431019)
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441212(CHEMBL2431028)
Affinity DataIC50: 651nMAssay Description:Inhibition of ADAM-17 in human A2774 cells assessed as inhibition of EGF-induced sALCAM release incubated for 30 mins prior to EGF induction measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441214(CHEMBL2431026)
Affinity DataIC50: 825nMAssay Description:Inhibition of ADAM-17 in human A2780 cells assessed as inhibition of pervanadate-induced sALCAM release incubated for 30 mins prior to pervanadate in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441215(CHEMBL2431021)
Affinity DataIC50: 840nMAssay Description:Inhibition of ADAM-17 in human A2780 cells assessed as inhibition of pervanadate-induced sALCAM release incubated for 30 mins prior to pervanadate in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441212(CHEMBL2431028)
Affinity DataIC50: 845nMAssay Description:Inhibition of ADAM-17 in human A2780 cells assessed as inhibition of EGF-induced sALCAM release incubated for 30 mins prior to EGF induction measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441219(CHEMBL2431020)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441223(CHEMBL2431016)
Affinity DataIC50: 940nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)
Affinity DataIC50: 966nMAssay Description:Inhibition of ADAM-17 in human SKOV3 cells transfected with luciferase gene assessed as inhibition of EGF-induced sALCAM release incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441214(CHEMBL2431026)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of ADAM-17 in human A2774 cells assessed as inhibition of pervanadate-induced sALCAM release incubated for 30 mins prior to pervanadate in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50314222((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of ADAM-17 in human A2780 cells assessed as inhibition of EGF-induced sALCAM release incubated for 30 mins prior to EGF induction measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441224(CHEMBL2431015)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441221(CHEMBL2431018)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441214(CHEMBL2431026)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of ADAM-17 in human SKOV3 cells transfected with luciferase gene assessed as inhibition of pervanadate-induced sALCAM release incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441222(CHEMBL2431017)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441212(CHEMBL2431028)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of ADAM-17 in human SKOV3 cells transfected with luciferase gene assessed as inhibition of EGF-induced sALCAM release incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441215(CHEMBL2431021)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of ADAM-17 in human SKOV3 cells transfected with luciferase gene assessed as inhibition of pervanadate-induced sALCAM release incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50441213(CHEMBL2431027)
Affinity DataIC50: 5.64E+3nMAssay Description:Inhibition of ADAM-17 in human SKOV3 cells transfected with luciferase gene assessed as inhibition of EGF-induced sALCAM release incubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441226(CHEMBL2431031)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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