Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 21
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65531BDBM65531((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-oxo-1-...)
Affinity DataIC50: 967nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65541BDBM65541((S)-4-(3-(2-((4-fluorobenzyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50: 1.07E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65541BDBM65541((S)-4-(3-(2-((4-fluorobenzyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50: 1.21E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65537BDBM65537((S)-4-(3-(2-((3-chlorophenyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50: 1.28E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65535BDBM65535((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-((2-hy...)
Affinity DataIC50: 1.31E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65544BDBM65544((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-oxo-1-...)
Affinity DataIC50: 1.32E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65523BDBM65523((S)-4-(3-(2-((2-fluorophenyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50: 1.33E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65529BDBM65529((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-oxo-1-...)
Affinity DataIC50: 1.34E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.41E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65528BDBM65528((S)-4-(3-(2-(furan-2-ylamino)-2-oxo-1-phenylethyl)...)
Affinity DataIC50: 1.46E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65521BDBM65521((S)-4-(3-(2-(benzylamino)-2-oxo-1-phenylethyl)urei...)
Affinity DataIC50: 1.51E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65547BDBM65547(phenylglycine containing lead compound (4h))
Affinity DataIC50: 1.52E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65539BDBM65539((S)-4-(3-(2-((3-fluoro-4-methoxyphenyl)amino)-2-ox...)
Affinity DataIC50: 1.54E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65545BDBM65545((S)-4-(3-(2-((2,4-dichlorophenyl)amino)-2-oxo-1-ph...)
Affinity DataIC50: 1.57E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65538BDBM65538((S)-4-(3-(2-((3,5-dimethylphenyl)amino)-2-oxo-1-ph...)
Affinity DataIC50: 1.66E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65525BDBM65525((S)-4-(3-(2-((4-fluorophenyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50: 1.77E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65534BDBM65534((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-((2-me...)
Affinity DataIC50: 1.77E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65530BDBM65530((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-(napht...)
Affinity DataIC50: 1.79E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65543BDBM65543((S)-4-(3-(2-((2,6-diisopropylphenyl)amino)-2-oxo-1...)
Affinity DataIC50: 1.79E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65532BDBM65532((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-oxo-1-...)
Affinity DataIC50: 1.87E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University

LigandChemical structure of BindingDB Monomer ID 65526BDBM65526((S)-4-(3-(2-((4-(tert-butyl)phenyl)amino)-2-oxo-1-...)
Affinity DataIC50: 2.34E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed