Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 21
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65531((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-oxo-1-...)
Affinity DataIC50:  967nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65541((S)-4-(3-(2-((4-fluorobenzyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50:  1.07E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65541((S)-4-(3-(2-((4-fluorobenzyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50:  1.21E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65537((S)-4-(3-(2-((3-chlorophenyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50:  1.28E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65535((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-((2-hy...)
Affinity DataIC50:  1.31E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65544((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-oxo-1-...)
Affinity DataIC50:  1.32E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65523((S)-4-(3-(2-((2-fluorophenyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50:  1.33E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65529((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-oxo-1-...)
Affinity DataIC50:  1.34E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.41E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65528((S)-4-(3-(2-(furan-2-ylamino)-2-oxo-1-phenylethyl)...)
Affinity DataIC50:  1.46E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65521((S)-4-(3-(2-(benzylamino)-2-oxo-1-phenylethyl)urei...)
Affinity DataIC50:  1.51E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65547(phenylglycine containing lead compound (4h))
Affinity DataIC50:  1.52E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65539((S)-4-(3-(2-((3-fluoro-4-methoxyphenyl)amino)-2-ox...)
Affinity DataIC50:  1.54E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65545((S)-4-(3-(2-((2,4-dichlorophenyl)amino)-2-oxo-1-ph...)
Affinity DataIC50:  1.57E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65538((S)-4-(3-(2-((3,5-dimethylphenyl)amino)-2-oxo-1-ph...)
Affinity DataIC50:  1.66E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65525((S)-4-(3-(2-((4-fluorophenyl)amino)-2-oxo-1-phenyl...)
Affinity DataIC50:  1.77E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65534((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-((2-me...)
Affinity DataIC50:  1.77E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65530((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-(napht...)
Affinity DataIC50:  1.79E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65543((S)-4-(3-(2-((2,6-diisopropylphenyl)amino)-2-oxo-1...)
Affinity DataIC50:  1.79E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65532((S)-N-(6-(hydroxyamino)-6-oxohexyl)-4-(3-(2-oxo-1-...)
Affinity DataIC50:  1.87E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Qingdao University

LigandPNGBDBM65526((S)-4-(3-(2-((4-(tert-butyl)phenyl)amino)-2-oxo-1-...)
Affinity DataIC50:  2.34E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed