Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50043478 Sort by
TargetMacrophage metalloelastase(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant MMP-12 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 30 mins prior to substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM23274(BMCL176463 Compound 2 | BMC173072 Compound 2 | (2E...)
Affinity DataIC50: 410nMAssay Description:Inhibition of Clostridium botulinum BoNT/AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 410nMAssay Description:Inhibition of 5-LOX (unknown origin)-mediated leukotriene (LT)B4 biosynthesisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed