Found 17 Enz. Inhib. hit(s) with all data for entry = 50043532 Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of [1,2,-3H]-cortisone to [3H]cortisol preincubated for ...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of [1,2,-3H]-cortisone to [3H]cortisol preincubated for ...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of [1,2,-3H]-cortisone to [3H]cortisol preincubated for ...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at human recombinant mineralocorticoid receptor expressed in HEK-293 cells after 24 hrs assessed as inhibition of aldosterone-ind...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 5.85E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+4nMAssay Description:Antagonist activity at human recombinant mineralocorticoid receptor expressed in HEK-293 cells after 24 hrs assessed as inhibition of aldosterone-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:Transactivation of human recombinant mineralocorticoid receptor expressed in HEK-293 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Transactivation of wild-type human recombinant mineralocorticoid receptor expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+4nMAssay Description:Transactivation of human recombinant mineralocorticoid receptor expressed in HEK-293 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
