Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 6079
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  42nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  114nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107675(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)
Affinity DataIC50:  142nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107677(1-(3-Chloro-4-fluorophenyl)-3-(3-(methyl (2-methyl...)
Affinity DataIC50:  232nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107675(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)
Affinity DataIC50:  271nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107673(1-(3-(6-Chloro-2-methylpyrimidin-4-ylamino)phenyl)...)
Affinity DataIC50:  298nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107677(1-(3-Chloro-4-fluorophenyl)-3-(3-(methyl (2-methyl...)
Affinity DataIC50:  366nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107674(1-(3-Chloro-4-fluorophenyl)-3-(3-(2-methyl- 6-morp...)
Affinity DataIC50:  626nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107673(1-(3-(6-Chloro-2-methylpyrimidin-4-ylamino)phenyl)...)
Affinity DataIC50:  722nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107674(1-(3-Chloro-4-fluorophenyl)-3-(3-(2-methyl- 6-morp...)
Affinity DataIC50:  1.07E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107678(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(methy...)
Affinity DataIC50:  1.37E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107678(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(methy...)
Affinity DataIC50:  1.37E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107679(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(methy...)
Affinity DataIC50:  4.99E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107679(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(methy...)
Affinity DataIC50:  5.28E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107676(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)
Affinity DataIC50:  7.17E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry

LigandPNGBDBM107676(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed