Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50043636
TargetProstaglandin E synthase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443967(CHEMBL3092283)
Affinity DataIC50: 800nMAssay Description:Inhibition of mPGES-1 in human HeLa cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443968(CHEMBL3092271)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mPGES-1 in human HeLa cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443969(CHEMBL3092270)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of mPGES-1 in human HeLa cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443970(CHEMBL3092269)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of mPGES-1 in human HeLa cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50443971(CHEMBL3092263 | US9247759, 5-23)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of mPGES-1 in human HeLa cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM60947(US9247759, compound C | BDBM50443972)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of mPGES-1 in human HeLa cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed