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Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50043648
TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444153(CHEMBL3093304)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444147(CHEMBL3093396)
Affinity DataIC50:  88nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444138(CHEMBL3093392)
Affinity DataIC50:  110nMAssay Description:Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444140(CHEMBL3093394)
Affinity DataIC50:  120nMAssay Description:Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444141(CHEMBL3093393)
Affinity DataIC50:  130nMAssay Description:Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444150(CHEMBL3093307)
Affinity DataIC50:  131nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444148(CHEMBL3093309)
Affinity DataIC50:  156nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444144(CHEMBL3093302)
Affinity DataIC50:  184nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444158(CHEMBL3093401)
Affinity DataIC50:  209nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444139(CHEMBL3093395)
Affinity DataIC50:  214nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444141(CHEMBL3093393)
Affinity DataIC50:  219nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444149(CHEMBL3093308)
Affinity DataIC50:  236nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444151(CHEMBL3093306)
Affinity DataIC50:  236nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444138(CHEMBL3093392)
Affinity DataIC50:  237nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444138(CHEMBL3093392)
Affinity DataIC50:  250nMAssay Description:Inhibition of full length human endothelial lipase transfected in HEK293 cells using PED-A1 as substrate preincubated for 30 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444140(CHEMBL3093394)
Affinity DataIC50:  252nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444154(CHEMBL3093303)
Affinity DataIC50:  259nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444139(CHEMBL3093395)
Affinity DataIC50:  330nMAssay Description:Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444143(CHEMBL3093391)
Affinity DataIC50:  366nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444152(CHEMBL3093305)
Affinity DataIC50:  372nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444146(CHEMBL3093398)
Affinity DataIC50:  499nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444142(CHEMBL3093399)
Affinity DataIC50:  551nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444160(CHEMBL3093397)
Affinity DataIC50:  570nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444159(CHEMBL3093400)
Affinity DataIC50:  659nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444145(CHEMBL3093405)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444155(CHEMBL3093404)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444161(CHEMBL3093301)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444153(CHEMBL3093304)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatic triacylglycerol lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444145(CHEMBL3093405)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatic triacylglycerol lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444144(CHEMBL3093302)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatic triacylglycerol lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444138(CHEMBL3093392)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444157(CHEMBL3093402)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444156(CHEMBL3093403)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444145(CHEMBL3093405)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444162(CHEMBL3093300)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatic triacylglycerol lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444141(CHEMBL3093393)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatic triacylglycerol lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444140(CHEMBL3093394)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444152(CHEMBL3093305)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444138(CHEMBL3093392)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatic triacylglycerol lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444139(CHEMBL3093395)
Affinity DataIC50:  2.33E+4nMAssay Description:Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatic triacylglycerol lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444143(CHEMBL3093391)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444151(CHEMBL3093306)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444150(CHEMBL3093307)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444147(CHEMBL3093396)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444154(CHEMBL3093303)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444148(CHEMBL3093309)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444139(CHEMBL3093395)
Affinity DataIC50:  4.52E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444149(CHEMBL3093308)
Affinity DataIC50:  4.99E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444141(CHEMBL3093393)
Affinity DataIC50:  7.63E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444140(CHEMBL3093394)
Affinity DataIC50:  7.72E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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