Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50043685 Sort by
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444605(CHEMBL3099899)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human orexin-2 receptor assessed as inhibition of orexin-A-induced intracellular calcium mobilization after 30 mins by cell-ba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444605(CHEMBL3099899)
Affinity DataIC50: 292nMAssay Description:Antagonist activity at human orexin-1 receptor assessed as inhibition of orexin-A-induced intracellular calcium mobilization after 30 mins by cell-ba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444605(CHEMBL3099899)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444606(CHEMBL3099898)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444611(CHEMBL3099893)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444610(CHEMBL3099894)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444607(CHEMBL3099897)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444618(CHEMBL3099886)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444612(CHEMBL3099892)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444615(CHEMBL3099889)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444609(CHEMBL3099895)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444620(CHEMBL3099884)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444613(CHEMBL3099891)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444616(CHEMBL3099888)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444614(CHEMBL3099890)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444617(CHEMBL3099887)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444605(CHEMBL3099899)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444608(CHEMBL3099896)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444612(CHEMBL3099892)
Affinity DataKi:  236nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444618(CHEMBL3099886)
Affinity DataKi:  273nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444611(CHEMBL3099893)
Affinity DataKi:  462nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444619(CHEMBL3099885)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444607(CHEMBL3099897)
Affinity DataKi:  747nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444615(CHEMBL3099889)
Affinity DataKi:  833nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444610(CHEMBL3099894)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444606(CHEMBL3099898)
Affinity DataKi:  1.09E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444613(CHEMBL3099891)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444619(CHEMBL3099885)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444616(CHEMBL3099888)
Affinity DataKi:  2.98E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444614(CHEMBL3099890)
Affinity DataKi:  3.35E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444620(CHEMBL3099884)
Affinity DataKi:  3.55E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444609(CHEMBL3099895)
Affinity DataKi:  5.15E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444617(CHEMBL3099887)
Affinity DataKi:  7.25E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444608(CHEMBL3099896)
Affinity DataKi:  6.50E+4nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed