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Found 23 Enz. Inhib. hit(s) with all data for entry = 50043797
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446472(CHEMBL3110021 | US9765054, Compound 41B)
Affinity DataIC50:  60nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50245989(1-(5-(3-((4-(1,3,4-oxadiazol-2-yl)phenoxy)methyl)-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446472(CHEMBL3110021 | US9765054, Compound 41B)
Affinity DataIC50:  400nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446472(CHEMBL3110021 | US9765054, Compound 41B)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446474(CHEMBL3109980 | US9765054, Compound 25e)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446475(CHEMBL3110001)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446479(CHEMBL3110015 | US9765054, Compound 50A)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446472(CHEMBL3110021 | US9765054, Compound 41B)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446473(CHEMBL3109983 | US9765054, Compound 33)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446476(CHEMBL3109993 | US9765054, Compound 28B)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446470(CHEMBL3109985 | US9765054, Compound 46)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446477(CHEMBL3110023 | US9765054, Compound 25b)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446478(CHEMBL3110016 | US9765054, Compound 50B)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446480(CHEMBL3110005)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446471(CHEMBL3109984 | US9765054, Compound 75a)
Affinity DataIC50: >3.90E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446482(CHEMBL3110003)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: >4.30E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446470(CHEMBL3109985 | US9765054, Compound 46)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant full length HDAC3-NCoR2 using Lys_Ac_AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446470(CHEMBL3109985 | US9765054, Compound 46)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446471(CHEMBL3109984 | US9765054, Compound 75a)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biofocus

Curated by ChEMBL
LigandPNGBDBM50446471(CHEMBL3109984 | US9765054, Compound 75a)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed