Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50001532
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 35nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016341(CHEMBL56005 | 2-(4-{4-[(2,4-Diamino-pteridin-6-ylm...)
Affinity DataIC50: 82nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016342(CHEMBL264245 | 2-[4-(4-{4-[(2,4-Diamino-pteridin-6...)
Affinity DataIC50: 90nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016343(CHEMBL54833 | 2-{4-[4-(4-{4-[(2,4-Diamino-pteridin...)
Affinity DataKi:  130nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016340(CHEMBL435778 | 2-[4-(4-{4-[4-(4-{4-[(2,4-Diamino-p...)
Affinity DataKi:  172nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016339(CHEMBL55167 | 2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteri...)
Affinity DataKi:  189nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016342(CHEMBL264245 | 2-[4-(4-{4-[(2,4-Diamino-pteridin-6...)
Affinity DataKi:  205nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016343(CHEMBL54833 | 2-{4-[4-(4-{4-[(2,4-Diamino-pteridin...)
Affinity DataIC50: 310nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016341(CHEMBL56005 | 2-(4-{4-[(2,4-Diamino-pteridin-6-ylm...)
Affinity DataKi:  336nMAssay Description:Compound was tested for its ability to inhibit thymidylate synthetase isolated from MTX-resistant Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016339(CHEMBL55167 | 2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteri...)
Affinity DataIC50: 540nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016340(CHEMBL435778 | 2-[4-(4-{4-[4-(4-{4-[(2,4-Diamino-p...)
Affinity DataIC50: 840nMAssay Description:Compound was tested for its ability to inhibit dihydrofolate reductase purified from murine L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed